Article
Genetic diversity and antiretroviral resistance-associated mutation profile of treated and naive HIV-1 infected patients from the Northwest and Southwest regions of Cameroon.
PloS one - 1 Jan 2019
Meriki Henry Dilonga, Tufon Kukwah Anthony, Anong Damian Nota, Atanga Pascal Nji, Anyangwe Irene Ane, Cho-Ngwa Fidelis, Nkuo-Akenji Theresa
Abstract excerpt
BACKGROUND: Antiretroviral therapy (ART) has improved the survival of HIV infected persons. However, rapid scale-up of ART and the high HIV-1 genetic variability, has greatly influenced the emergence of drug-resistant strains. This constitutes a potential threat to achieving the UNAIDS' 90-90-90 goals by 2020. We investigated the prevalent HIV-1 genotypes, drug resistance-associated mutations and assessed some...
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