Article

OCT4 Suppresses Metastasis in Breast Cancer Cells Through Activation of STAT3 Signaling

2020-09-04

Abstract excerpt

<title>Abstract</title> <p>Background: Metastatic breast cancer is the major cause of death in breast cancer patients. Activation of epithelial-mesenchymal transition (EMT) induces migration and invasion of breast cancer cells (BCCs). OCT4 (<italic>POU5F1</italic>) is a key transcription factor for reprograming and plays an important role in self-renewal. Recent studies recovered OCT4 may correlate with cancer pr...

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Literature Corpus work: e922ecb8-10b4-5ade-8006-e5fac472b25f
DOI: 10.21203/rs.3.rs-66884/v1

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