Article
Abnormal Expression of PICT-1 and Its Codon 389 Polymorphism Is a Risk Factor for Human Endometrial Cancer.
Oncology - 1 Jan 2018
Yoshimoto Masafumi, Tokuda Aoi, Nishiwaki Kunihiko, Sengoku Kazuo, Yaginuma Yuji
Abstract excerpt
OBJECTIVE: The protein interacting with carboxyl terminus-1 (PICT-1) gene has been implicated as a tumor suppressor gene, and its alterations have been reported in several cancers. This study investigated the association of PICT-1 alterations with endometrial carcinogenesis. METHODS: We analyzed the entire coding region of the PICT-1 gene using polymerase chain reaction-single-strand conformation polymorphism and...
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