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Article

Single nucleotide polymorphisms of PIN1 promoter region and cancer risk: evidence from a meta-analysis.

PloS one - 1 Jan 2013

Peng Jing-Jing, Wei Dong, Li Dong, Fu Zeng-Qiang, Tan Yong, Xu Tao, Zhou Jing-Jun, Zhang Tao

Abstract excerpt

BACKGROUND: Peptidylprolyl cis/trans isomerase NIMA-interacting 1 (PIN1) is involved in the process of tumorigenesis. The two single nucleotide polymorphisms (-677T>C, -842G>C) in the PIN1 promoter region have been suspected of being associated with cancer risk for years, but the conclusion is still inconclusive. METHODS: Eligible case-control studies were retrieved by searching databases and references of...

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Identifiers

PMID: 23976970
DOI: 10.1371/journal.pone.0070990
PMCID: PMC3745411

Genes

PIN1

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Single nucleotide polymorphisms of PIN1 promoter region and cancer risk: evidence from a meta-analysis.PMID 23976970Read ↗

The -842G/C polymorphisms of PIN1 contributes to cancer risk: a meta-analysis of 10 case-control studies.Semantic proximity Read ↗

The rs2233678 polymorphism in PIN1 promoter region reduced cancer risk: a meta-analysis.Semantic proximity Read ↗

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Association between PIN1 promoter polymorphisms and risk of nasopharyngeal carcinoma.Semantic proximity Read ↗

Pin1 promoter rs2233678 and rs2233679 polymorphisms in cancer: a meta-analysis.Semantic proximity Read ↗

Functional polymorphisms in PIN1 promoter and esophageal carcinoma susceptibility in Chinese population.Semantic proximity Read ↗

The Pin1 gene polymorphism and the susceptibility of oral squamous cell carcinoma in East China.Semantic proximity Read ↗

The polymorphism and haplotypes of PIN1 gene are associated with the risk of lung cancer in Southern and Eastern Chinese populations.Semantic proximity Read ↗

A novel functional variant (-842G>C) in the PIN1 promoter contributes to decreased risk of squamous cell carcinoma of the head and neck by diminishing the promoter activity.Semantic proximity Read ↗

Functional polymorphism of PIN1 rs2233679 is associated with the progression of CIN to early cervical cancer in Hunan Chinese.Semantic proximity Read ↗

[A Meta-analysis of Pin1 gene polymorphism at -842 loci and cancer susceptibility].Semantic proximity Read ↗

Analysis of peptidyl-propyl-cis/trans isomerase 1 (PIN1) gene -842(G > C) and -667(T > C) polymorphic variants in relation to breast cancer risk and clinico-pathological parameters.Semantic proximity Read ↗

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