Article
Sequence-Based Analysis of Lipid-Related Metabolites in a Multiethnic Study.
Genetics - 1 Jun 2018
Feofanova Elena V, Yu Bing, Metcalf Ginger A, Liu Xiaoming, Muzny Donna, Below Jennifer E, Wagenknecht Lynne E, Gibbs Richard A, Morrison Alanna C, Boerwinkle Eric
Abstract excerpt
Small molecule lipid-related metabolites are important components of fatty acid and steroid metabolism-two important contributors to human health. This study investigated the extent to which rare and common genetic variants spanning the human genome influence the lipid-related metabolome. Sequence data from 1552 European-Americans (EA) and 1872 African-Americans (AA) were analyzed to examine the impact of common...
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