Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

pyNBS: a Python implementation for network-based stratification of tumor mutations.

Bioinformatics (Oxford, England) - 15 Aug 2018

Huang Justin K, Jia Tongqiu, Carlin Daniel E, Ideker Trey

Abstract excerpt

Summary: We present pyNBS: a modularized Python 2.7 implementation of the network-based stratification (NBS) algorithm for stratifying tumor somatic mutation profiles into molecularly and clinically relevant subtypes. In addition to release of the software, we benchmark its key parameters and provide a compact cancer reference network that increases the significance of tumor stratification using the NBS...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Mutation
Share to Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Sequence Analysis, DNA

Share to Software

Source

Open in PubMed Open full text

Identifiers

PMID: 29608663
DOI: 10.1093/bioinformatics/bty186
PMCID: PMC6084608

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

pyNBS: a Python implementation for network-based stratification of tumor mutations.PMID 29608663Read ↗

Network-based stratification of tumor mutations.Semantic proximity Read ↗

Integrating genetic and gene expression data in network-based stratification analysis of cancersSemantic proximity Read ↗

A network-based deep learning methodology for stratification of tumor mutationsSemantic proximity Read ↗

Classifying tumors by supervised network propagation.Semantic proximity Read ↗

Mutational interactions define novel cancer subgroupsSemantic proximity Read ↗

Network-based stratification analysis of 13 major cancer types using mutations in panels of cancer genes.Semantic proximity Read ↗

PathScore: a web tool for identifying altered pathways in cancer dataSemantic proximity Read ↗

Network-Based Stratification Refines Stratification of Intermediate-Risk Acute Myeloid Leukemia SamplesSemantic proximity Read ↗

A network-based deep learning model integrating subclonal architecture for therapy response prediction in cancerSemantic proximity Read ↗

NetNorM: Capturing cancer-relevant information in somatic exome mutation data with gene networks for cancer stratification and prognosis.Semantic proximity Read ↗

PathScore: a web tool for identifying altered pathways in cancer data.Semantic proximity Read ↗

A Novel Affordable and Reliable Framework for Accurate Detection and Comprehensive Analysis of Somatic Mutations in Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.