Article
Classifying tumors by supervised network propagation.
Bioinformatics (Oxford, England) - 1 Jul 2018
Zhang Wei, Ma Jianzhu, Ideker Trey
Abstract excerpt
Motivation: Network propagation has been widely used to aggregate and amplify the effects of tumor mutations using knowledge of molecular interaction networks. However, propagating mutations through interactions irrelevant to cancer leads to erosion of pathway signals and complicates the identification of cancer subtypes. Results: To address this problem we introduce a propagation algorithm, Network-Based...
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