Article
Network-based stratification analysis of 13 major cancer types using mutations in panels of cancer genes.
BMC genomics - 1 Jan 2015
Zhong Xue, Yang Hushan, Zhao Shuyang, Shyr Yu, Li Bingshan
Abstract excerpt
BACKGROUND: Cancers are complex diseases with heterogeneous genetic causes and clinical outcomes. It is critical to classify patients into subtypes and associate the subtypes with clinical outcomes for better prognosis and treatment. Large-scale studies have comprehensively identified somatic mutations across multiple tumor types, providing rich datasets for classifying patients based on genomic mutations. One...
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