Article
Mutations affecting cooperative DNA binding of phage HK022 CI repressor.
Journal of molecular biology - 29 May 1998
Mao C, Little J W
Abstract excerpt
Cooperative protein-DNA interactions play critical roles in gene regulation in all organisms. Among the best-studied cooperative interactions is that of phage lambda repressor, which binds cooperatively to two adjacent operators. Similar cooperative interactions are also shown by several other lambdoid phage repressors, including HK022 CI repressor, which we study here. This protein has a much higher degree of...
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