Mutations affecting cooperative DNA binding of phage HK022 CI repressor.

doi:10.1006/jmbi.1998.1725

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Article

Mutations affecting cooperative DNA binding of phage HK022 CI repressor.

Journal of molecular biology - 29 May 1998

Mao C, Little J W

Abstract excerpt

Cooperative protein-DNA interactions play critical roles in gene regulation in all organisms. Among the best-studied cooperative interactions is that of phage lambda repressor, which binds cooperatively to two adjacent operators. Similar cooperative interactions are also shown by several other la...

Topics

Bacteriophage lambda
DNA Footprinting
DNA-Binding Proteins
Dimerization
Escherichia coli
Gene Expression Regulation, Viral
Mutation
Protein Conformation
Repressor Proteins
Viral Proteins
Viral Regulatory and Accessory Proteins

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