Article
Assessing melanoma prognosis: the interplay between patient profiles, survival, and BRAF, NRAS, KIT, and TWT mutations in a retrospective multi-study analysis.
Melanoma research - 1 Oct 2024
Kodali Nilesh, Bhattaru Abhijit, Blanchard Isabella, Sharma Yash, Lipner Shari R
Abstract excerpt
The incidence and prevalence of melanoma are increasing globally, presenting a significant public health concern. The main genetic drivers of melanoma include BRAF, NRAS, KIT and triple wild-type (TWT) mutations. Little is known about the effects of these mutations on outcomes in terms of demographics and patient characteristics. We examined differences in melanoma mortality risk and mutation count across...
Topics
- Humans
- Melanoma
- Male
- Female
- Proto-Oncogene Proteins B-raf
- Prognosis
- Mutation
- Retrospective Studies
- Skin Neoplasms
- Middle Aged
- GTP Phosphohydrolases