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Mutational concordance between primary and metastatic melanoma: a next-generation sequencing approach

28 Aug 2019

Abstract excerpt

BACKGROUND: Cutaneous malignant melanoma (CMM) is one of the most common skin cancers worldwide. Limited information is available in the current scientific literature on the concordance of genetic alterations between primary and metastatic CMM. In the present study, we performed next-generation sequencing (NGS) analysis of the main genes participating in melanoma pathogenesis and progression, among paired primary...

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PMID: 31455347
DOI: 10.1186/s12967-019-2039-4

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