Association of rs1137101 polymorphism in LEPR and susceptibility to knee osteoarthritis in a Northwest Chinese Han population.

doi:10.1186/s12891-016-1162-0

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Article

Association of rs1137101 polymorphism in LEPR and susceptibility to knee osteoarthritis in a Northwest Chinese Han population.

BMC musculoskeletal disorders - 25 Jul 2016

Yang Jianhui, Du Heng, Lv Jianguo, Zhang Lianhe

Abstract excerpt

BACKGROUND: Osteoarthritis (OA) is a complex arthritic condition in which the genetic factor plays a crucial role. A single nucleotide polymorphism (SNP), rs1137101 (Gln223Arg) of leptin receptor (LEPR) gene has been demonstrated to be associated with susceptibility to knee OA. However, this association in Chinese Han population has never been examined. The present study aimed to investigate whether Gln223Arg was...

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PMID: 27457563
DOI: 10.1186/s12891-016-1162-0
PMCID: PMC4960800

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LEPR

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