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Article

Loss of preimplantation embryo resulting from a Pum1 gene trap mutation.

Biochemical and biophysical research communications - 19 Jun 2015

Zhang Chenwang, Zhu Tong, Chen Yanmei, Xu Eugene Yujun

Abstract excerpt

Pumilio is a member of the highly conserved PUF family of RNA-binding proteins that function as a developmental regulator in diverse animal species. Two Pumilio genes, Pum1 and Pum2, have been identified in mammals and are found to be involved in sperm development, neuron development as well as human diseases such as neurodegeneration. Generation of animal models disrupting different parts of Pum protein could...

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Identifiers

PMID: 25896760
DOI: 10.1016/j.bbrc.2015.04.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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