Article
Celiac Diasease-associated lncRNA Named HCG14 Regulates NOD1 Expression in Intestinal Cells.
Journal of pediatric gastroenterology and nutrition - 1 Aug 2018
Santin Izortze, Jauregi-Miguel Amaia, Velayos Teresa, Castellanos-Rubio Ainara, Garcia-Etxebarria Koldo, Romero-Garmendia Irati, Fernandez-Jimenez Nora, Irastorza Iñaki, Castaño Luis, Bilbao Jose Ramón
Abstract excerpt
OBJECTIVE: The aim of the study is to identify additional celiac disease associated loci in the major histocompatibility complex (MHC) independent from classical HLA risk alleles (HLA-DR3-DQ2) and to characterize their potential functional impact in celiac disease pathogenesis at the intestinal level. METHODS: We performed a high-resolution single-nucleotide polymorphism (SNP) genotyping of the MHC region,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
