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Article

A long noncoding RNA associated with susceptibility to celiac disease.

Science (New York, N.Y.) - 1 Apr 2016

Castellanos-Rubio Ainara, Fernandez-Jimenez Nora, Kratchmarov Radomir, Luo Xiaobing, Bhagat Govind, Green Peter H R, Schneider Robert, Kiledjian Megerditch, Bilbao Jose Ramon, Ghosh Sankar

Abstract excerpt

Recent studies have implicated long noncoding RNAs (lncRNAs) as regulators of many important biological processes. Here we report on the identification and characterization of a lncRNA, lnc13, that harbors a celiac disease-associated haplotype block and represses expression of certain inflammatory genes under homeostatic conditions. Lnc13 regulates gene expression by binding to hnRNPD, a member of a family of...

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Identifiers

PMID: 27034373
DOI: 10.1126/science.aad0467
PMCID: PMC4994711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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