Article
Feature selection with interactions in logistic regression models using multivariate synergies for a GWAS application.
BMC genomics - 21 Mar 2018
Xu Easton Li, Qian Xiaoning, Yu Qilian, Zhang Han, Cui Shuguang
Abstract excerpt
BACKGROUND: Genotype-phenotype association has been one of the long-standing problems in bioinformatics. Identifying both the marginal and epistatic effects among genetic markers, such as Single Nucleotide Polymorphisms (SNPs), has been extensively integrated in Genome-Wide Association Studies (GWAS) to help derive "causal" genetic risk factors and their interactions, which play critical roles in life and disease...
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