Article
Sequencing the exons of human glucocorticoid receptor (NR3C1) gene in Han Chinese with high-altitude pulmonary edema.
Journal of physiological anthropology - 27 Mar 2018
Du Hui, Zhao Jing, Su Zhanhai, Liu Yongnian, Yang Yingzhong
Abstract excerpt
BACKGROUND: High-altitude pulmonary edema (HAPE) is a serious acute mountain sickness that mainly occurs in non-acclimatized individuals after rapid ascent to high altitude. The precise etiology of HAPE remains unclear. This study aimed to investigate whether NR3C1 gene polymorphism is associated with the susceptibility to HAPE. METHODS: The exons of NR3C1 gene were sequenced by a ABI 3730 DNA analyzer in 133...
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