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Article

Effects of the S42 residue of the H1N1 swine influenza virus NS1 protein on interferon responses and virus replication

27 Mar 2018

Abstract excerpt

BACKGROUND: The influenza A virus non-structural protein 1 (NS1) is a multifunctional protein that plays an important role in virus replication, virulence and inhibition of the host antiviral immune response. In the avian influenza virus or human influenza virus, specific amino acids of NS1 have been shown to be important for the virus to antagonize host antiviral defenses and promote viral replication. However,...

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PMID: 29587786
DOI: 10.1186/s12985-018-0971-1

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