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Article

Influenza virus NS1 protein mutations at position 171 impact innate interferon responses by respiratory epithelial cells.

Virus research - 15 Aug 2017

Plant Ewan P, Ilyushina Natalia A, Sheikh Faruk, Donnelly Raymond P, Ye Zhiping

Abstract excerpt

The influenza virus NS1 protein interacts with a wide range of proteins to suppress the host cell immune response and facilitate virus replication. The amino acid sequence of the 2009 pandemic virus NS1 protein differed from sequences of earlier related viruses. The functional impact of these differences has not been fully defined. Therefore, we made mutations to the NS1 protein based on these sequence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28757142
DOI: 10.1016/j.virusres.2017.07.021

Genes

STAT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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