Article
BRAF(V600E) mutation analysis from May-Grünwald Giemsa-stained cytological samples as an adjunct in identification of high-risk papillary thyroid carcinoma.
Endocrine pathology - 1 Dec 2011
Patel Aneeta, Klubo-Gwiezdzinska Joanna, Hoperia Victoria, Larin Alexander, Jensen Kirk, Bauer Andrew, Vasko Vasyl
Abstract excerpt
The BRAF(V600E) mutation is specific for thyroid papillary cancer (PTC) and correlates with PTCs invasiveness. This study investigated whether detection of BRAF(V600E) mutation can be performed on routinely stained FNABs. We also examined if establishment of the BRAF(V600E) mutation could help in identification of patients at higher risk for metastatic disease. DNA was isolated from 134 FNABs samples (20...
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