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NTRK1 Fusion in Glioblastoma Multiforme

19 Mar 2014

Abstract excerpt

Glioblastoma multiforme (GBM) is the most aggressive form of brain tumor, yet with no targeted therapy with substantial survival benefit. Recent studies on solid tumors showed that fusion genes often play driver roles and are promising targets for pharmaceutical intervention. To survey potential fusion genes in GBMs, we analysed RNA-Seq data from 162 GBM patients available through The Cancer Genome Atlas (TCGA),...

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PMID: 24647444
DOI: 10.1371/journal.pone.0091940

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