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Fusion Genes Altered in Adult Malignant Gliomas

4 Oct 2021

Abstract excerpt

Malignant gliomas are highly heterogeneous brain tumors in molecular genetic background. Despite the many recent advances in the understanding of this disease, patients with adult high-grade gliomas retain a notoriously poor prognosis. Fusions involving oncogenes have been reported in gliomas and may serve as novel therapeutic targets to date. Understanding the gene fusions and how they regulate oncogenesis and...

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PMID: 34671307
DOI: 10.3389/fneur.2021.715206

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