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Article

DNA methylation of microRNA-coding genes in non-small-cell lung cancer patients.

The Journal of pathology - 1 Aug 2018

Heller Gerwin, Altenberger Corinna, Steiner Irene, Topakian Thais, Ziegler Barbara, Tomasich Erwin, Lang György, End-Pfützenreuter Adelheid, Zehetmayer Sonja, Döme Balazs, Arns Britt-Madeleine, Klepetko Walter, Zielinski Christoph C, Zöchbauer-Müller Sabine

Abstract excerpt

Deregulated DNA methylation leading to transcriptional inactivation of certain genes occurs frequently in non-small-cell lung cancers (NSCLCs). As well as protein-coding genes, microRNA (miRNA)-coding genes may be targets for methylation in NSCLCs; however, the number of known methylated miRNA genes is still small. Thus, we investigated methylation of miRNA genes in primary tumour (TU) samples and corresponding...

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Identifiers

PMID: 29570800
DOI: 10.1002/path.5079
PMCID: PMC6055722

Genes

CCNE1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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