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Multiple gene methylation of nonsmall cell lung cancers evaluated with 3‐dimensional microarray

19 Feb 2008

Abstract excerpt

BACKGROUND: Aberrant DNA methylation of the CpG islands for cancer-related genes is among the earliest and most frequent alterations in cancer and may be useful for diagnosing cancer or evaluating recurrent disease. METHODS: In this study, a 3-dimensional (3-D), polyacrylamide gel-based DNA microarray coupled with linker-polymerase chain reaction (PCR) was developed to detect hypermethylation of CpG islands in...

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Share to Epigenetics and DNA Methylation
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PMID: 18286531
DOI: 10.1002/cncr.23312

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