Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel putative drivers revealed by targeted exome sequencing of advanced solid tumors.

PloS one - 1 Jan 2018

Pannuti Antonio, Filipovic Aleksandra, Hicks Chindo, Lefkowitz Elliot, Ptacek Travis, Stebbing Justin, Miele Lucio

Abstract excerpt

Next generation sequencing (NGS) is becoming increasingly integrated into oncological practice and clinical research. NGS methods have also provided evidence for clonal evolution of cancers during disease progression and treatment. The number of variants associated with response to specific therapeutic agents keeps increasing. However, the identification of novel driver mutations as opposed to passenger...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Breast Neoplasms
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Lung Neoplasms

Share to Neoplasm Staging

Share to Neuroendocrine Tumors

Share to Sarcoma

Source

Open in PubMed Open full text

Identifiers

PMID: 29570743
DOI: 10.1371/journal.pone.0194790
PMCID: PMC5865730

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel putative drivers revealed by targeted exome sequencing of advanced solid tumors.PMID 29570743Read ↗

Comprehensive Characterization of Cancer Driver Genes and Mutations.Semantic proximity Read ↗

Comprehensive identification of mutational cancer driver genes across 12 tumor types.Semantic proximity Read ↗

Next-Generation Sequencing in Oncology—A Guiding Compass for Targeted Therapy and Emerging ApplicationsSemantic proximity Read ↗

Understanding oncogenicity of cancer driver genes and mutations in the cancer genomics era.Semantic proximity Read ↗

IntOGen-mutations identifies cancer drivers across tumor types.Semantic proximity Read ↗

Deciphering oncogenic drivers: from single genes to integrated pathways.Semantic proximity Read ↗

Cancer driver mutations: predictions and reality.Semantic proximity Read ↗

Pan-Cancer Driver Mutation Signatures Define a Molecular Taxonomy of TumorsSemantic proximity Read ↗

Next generation sequencing: clinical applications in solid tumoursSemantic proximity Read ↗

OncoVar: an integrated database and analysis platform for oncogenic driver variants in cancers.Semantic proximity Read ↗

Oncogenic gene fusions in cancer: from biology to therapySemantic proximity Read ↗

Identifying driver mutations from sequencing data of heterogeneous tumors in the era of personalized genome sequencing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.