Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular Mechanisms of Photoaging in Human Skin In Vivo and Their Prevention by All-Trans Retinoic Acid

1 Jan 1999

Abstract excerpt

Solar UV radiation damages human skin, affecting skin tone and resiliency and leading to premature aging (photoaging), the symptoms of which include leathery texture, wrinkles, mottled pigmentation, laxity and sallowness. We propose that photoaging results largely from UV induction of matrix metalloproteinases (MMP) that degrade skin collagen. We find that pretreatment of human skin with all-trans retinoic acid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antioxidant Activity and Oxidative Stress
Share to Retinoids in leukemia and cellular processes
Share to Skin Protection and Aging

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10048311
DOI: 10.1562/0031-8655(1999)069<0154:mmopih>2.3.co;2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular Mechanisms of Photoaging in Human Skin In Vivo and Their Prevention by All-Trans Retinoic AcidPMID 10048311Read ↗

Molecular Mechanisms of Photoaging in Human Skin <i>In Vivo</i> and Their Prevention by All‐Trans Retinoic AcidSemantic proximity Read ↗

Molecular Mechanisms of Photoaging and its Prevention by Retinoic Acid: Ultraviolet Irradiation Induces MAP Kinase Signal Transduction Cascades that Induce Ap-1-Regulated Matrix Metalloproteinases that Degrade Human Skin In VivoSemantic proximity Read ↗

Photoaging Decoded: Extracellular Matrix Alterations and Mechanisms via Mitogen-Activated Protein Kinase/Matrix Metalloproteinase, Transforming Growth Factor-β Pathways, and Glycosaminoglycan MetabolismSemantic proximity Read ↗

Photoaging of human skinSemantic proximity Read ↗

Photoaging of the skin from phenotype to mechanisms.Semantic proximity Read ↗

New insights in photoaging, UVA induced damage and skin typesSemantic proximity Read ↗

Photoprotection beyond Ultraviolet Radiation – Effective Sun Protection Has to Include Protection against Infrared A Radiation-Induced Skin DamageSemantic proximity Read ↗

Upregulation of MMP12 and Its Activity by UVA1 in Human Skin: Potential Implications for PhotoagingSemantic proximity Read ↗

Human Skin Aging and the Anti-Aging Properties of RetinolSemantic proximity Read ↗

Inflammatory Molecules Associated with Ultraviolet Radiation-Mediated Skin AgingSemantic proximity Read ↗

Low to Moderate Doses of Infrared A Irradiation Impair Extracellular Matrix Homeostasis of the Skin and Contribute to Skin PhotodamageSemantic proximity Read ↗

Antiphotoaging Effect of 3,5-Dicaffeoyl-epi-quinic Acid against UVA-Induced Skin Damage by Protecting Human Dermal Fibroblasts In VitroSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.