Single-nucleotide polymorphism (rs11204981) in filaggrin gene and its functional significance for asthma among children with eczema.

doi:10.15407/fz62.03.003

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Single-nucleotide polymorphism (rs11204981) in filaggrin gene and its functional significance for asthma among children with eczema.

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) - 1 Jan 2000

Pavlyk O, Iemets O, Stroy D, Volosovets O, Kryvopustov S, Dosenko V

Abstract excerpt

The aim of this study was to determine whether SNP in filaggrin gene and expression of filaggrin mRNA in buccal epithelium are associated with childhood eczema and with the phenotype of childhood eczema combined with asthma. Genotyping for FLG (rs11204981) was performed in the following populations: patients with asthma (n = 99); ages 5-18 years (8 ± 2.1), and control group (n = 98); ages 5–18 years (12 ± 2.1) by...

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PMID: 29569866
DOI: 10.15407/fz62.03.003

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