Article
Filaggrin gene polymorphisms in Indian children with atopic dermatitis: A cross-sectional multicentre study.
Indian journal of dermatology, venereology and leprology - 1 Jan 2000
Srinivas Sahana M, Dhar Sandipan, Gowdra Aruna, Saha Abhijit, Sundararajan Lakshmi, Geetha Thenral S, Banerjee Raghubir, Malakar Rajib, Sil Amrita, Lakshminarayana Shyam Prasad Arakali
Abstract excerpt
Background Filaggrin (FLG) gene encoding the protein filaggrin plays an important role in barrier function of the skin and its alteration is a predisposing factor for atopic dermatitis. FLG gene variants result in absent or decreased filaggrin protein. Worldwide, the prevalence of FLG variants ranges from 14 to 56%. FLG null variants are distinct in each population. Objectives To study the FLG gene polymorphisms...
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