Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical features of children with atopic dermatitis according to filaggrin gene variants.

Allergologia et immunopathologia - 1 Jan 2021

Arghavan Ziaali, Laleh Sharifi, Shahram Teimourian, Bita Hasani, Anna Isaian, Mansoureh Shariat

Abstract excerpt

BACKGROUND: Filament aggregating protein (Filaggrin) is a skeletal cell component that provides a protective function for the epidermis. Mutations of the filaggrin gene (FLG) cause a loss of filaggrin protein. These mutations are seen in 50% of atopic dermatitis (AD). The aim of the study was to investigate the polymorphisms and mutations of the FLG in Iranian children with AD. MATERIALS AND METHODS: This project...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dermatitis, Atopic
Share to Eczema
Share to Filaggrin Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin E

Share to Intermediate Filament Proteins

Share to Mutation

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 34224231
DOI: 10.15586/aei.v49i4.209

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical features of children with atopic dermatitis according to filaggrin gene variants.PMID 34224231Read ↗

Clinical characteristics of Korean patients with filaggrin-related atopic dermatitis.Semantic proximity Read ↗

Predictors of atopic dermatitis phenotypes and severity: roles of serum immunoglobulins and filaggrin gene mutation R501X.Semantic proximity Read ↗

Filaggrin polymorphism P478S, IgE level, and atopic phenotypes.Semantic proximity Read ↗

Filaggrin gene polymorphisms in Indian children with atopic dermatitis: A cross-sectional multicentre study.Semantic proximity Read ↗

The Genetics and Epigenetics of Atopic Dermatitis-Filaggrin and Other Polymorphisms.Semantic proximity Read ↗

Filaggrin gene defects and the risk of developing allergic disorders.Semantic proximity Read ↗

Filaggrin mutations and Molluscum contagiosum skin infection in patients with atopic dermatitis.Semantic proximity Read ↗

Genetics of Atopic Dermatitis: From DNA Sequence to Clinical RelevanceSemantic proximity Read ↗

Atopic Dermatitis: Disease Background and Risk Factors.Semantic proximity Read ↗

An update on the genetics of atopic dermatitis: scratching the surface in 2009.Semantic proximity Read ↗

Filaggrin loss-of-function variants are associated with atopic dermatitis phenotypes in a diverse, early-life prospective cohort.Semantic proximity Read ↗

Mutations in the filaggrin gene in Han Chinese patients with atopic dermatitis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.