Article
Wnt3 and Gata4 regulate axon regeneration in adult mouse DRG neurons.
Biochemical and biophysical research communications - 5 May 2018
Duan Run-Shan, Liu Pei-Pei, Xi Feng, Wang Wei-Hua, Tang Gang-Bin, Wang Rui-Ying, Saijilafu, Liu Chang-Mei
Abstract excerpt
Neurons in the adult central nervous system (CNS) have a poor intrinsic axon growth potential after injury, but the underlying mechanisms are largely unknown. Wingless-related mouse mammary tumor virus integration site (WNT) family members regulate neural stem cell proliferation, axon tract and forebrain development in the nervous system. Here we report that Wnt3 is an important modulator of axon regeneration....
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