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Article

Evaluation of the cobas® GT hepatitis C virus genotyping assay in G1-6 viruses including low viral loads and LiPA failures.

PloS one - 1 Jan 2018

Némoz Benjamin, Roger Léa, Leroy Vincent, Poveda Jean-Dominique, Morand Patrice, Larrat Sylvie

Abstract excerpt

Direct-acting antiviral (DAA) drug performances depend on the viral genotype. So international recommendations give typing of the virus a prerequisite for treatment choice and patient management. Commercially available HCV genotyping kits are scarce and this analysis is often in-house using tedious PCRs and Sanger sequencing, leading to a lack of standardization. A newly commercialized HCV genotyping assay based...

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Share to Asymptomatic Infections
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis C, Chronic

Share to Reagent Kits, Diagnostic

Share to Real-Time Polymerase Chain Reaction

Share to Sequence Analysis, RNA

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Identifiers

PMID: 29566005
DOI: 10.1371/journal.pone.0194396
PMCID: PMC5864039

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