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Evaluation of the new cobas® HCV genotyping test based on real-time PCRs of three different HCV genome regions.

Clinical chemistry and laboratory medicine - 1 Mar 2017

Stelzl Evelyn, Appel Hannah M, Mehta Rochak, Marins Ed G, Berg Jörg, Paar Christian, Zurl Hanna, Santner Brigitte I, Kessler Harald H

Abstract excerpt

BACKGROUND: Determination of the hepatitis C virus (HCV) genotype and discrimination between HCV subtypes 1a and 1b is still mandatory prior to anti-HCV treatment initiation. The aim of this study was to evaluate the performance of the recently introduced cobas® HCV GT assay (Roche) and to compare it to two comparator assays. METHODS: The cobas® HCV GT assay is based on primer-specific real-time polymerase chain...

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PMID: 27740913
DOI: 10.1515/cclm-2016-0620

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