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Article

Influence of the DRD2/ANKK1 Taq1A polymorphism on caudate volume in older adults without dementia.

Brain structure & function - 1 Jul 2018

Li Xin, Papenberg Goran, Kalpouzos Grégoria, Bäckman Lars, Persson Jonas

Abstract excerpt

Dopaminergic neuromodulation is critically important for brain and cognitive integrity. The DRD2/ANKK1 Taq1A polymorphism is associated with striatal dopamine (DA) D2 receptor availability. Some previous studies have found that the A allele of the Taq1A polymorphism influences brain structure, but the results are inconsistent, likely due to population heterogeneity and small sample sizes. We investigated the...

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Identifiers

PMID: 29564530
DOI: 10.1007/s00429-018-1650-0
PMCID: PMC5995982

Genes

DRD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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