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Article

Influences of a DRD2 polymorphism on updating of long-term memory representations and caudate BOLD activity: magnification in aging.

Human brain mapping - 1 Apr 2015

Persson Jonas, Rieckmann Anna, Kalpouzos Grégoria, Fischer Håkan, Bäckman Lars

Abstract excerpt

A number of genetic polymorphisms are related to individual differences in cognitive performance. Striatal dopamine (DA) functions, associated with cognitive performance, are linked to the TaqIA polymorphism of the DRD2/ANKK1 gene. In humans, presence of an A1 allele of the DRD2/ANKK1-TaqIA polymorphism is related to reduced density of striatal DA D2 receptors. The resource-modulation hypothesis assumes that...

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Identifiers

PMID: 25486867
DOI: 10.1002/hbm.22704
PMCID: PMC6869631

Genes

DRD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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