Article
Planar Cell Polarity Signaling in Mammalian Cardiac Morphogenesis.
Pediatric cardiology - 1 Jun 2018
Li Ding, Wang Jianbo
Abstract excerpt
The mammalian heart is the first organ to form and is critical for embryonic survival and development. With an occurrence of 1%, congenital heart defects (CHDs) are also the most common birth defects in humans, and major cause of childhood morbidity and mortality (Hoffman and Kaplan in J Am Coll Cardiol 39(12):1890-1900, 2002; Samanek in Cardiol Young 10(3):179-185, 2000). Understanding how the heart forms will...
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