Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

EFF-1 fusogen promotes phagosome sealing during cell process clearance in Caenorhabditis elegans.

Nature cell biology - 1 Apr 2018

Ghose Piya, Rashid Alina, Insley Peter, Trivedi Meera, Shah Pavak, Singhal Anupriya, Lu Yun, Bao Zhirong, Shaham Shai

Abstract excerpt

Phagocytosis of dying cells is critical in development and immunity1-3. Although proteins for recognition and engulfment of cellular debris following cell death are known4,5, proteins that directly mediate phagosome sealing are uncharacterized. Furthermore, whether all phagocytic targets are cleared using the same machinery is unclear. Degeneration of morphologically complex cells, such as neurons, glia and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Caenorhabditis elegans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Caenorhabditis elegans Proteins

Share to Cell Death

Share to Phagocytes

Share to Phagocytosis

Share to Phagosomes

Share to Pseudopodia

Source

Open in PubMed Open full text

Identifiers

PMID: 29556089
DOI: 10.1038/s41556-018-0068-5
PMCID: PMC5876135

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

EFF-1 fusogen promotes phagosome sealing during cell process clearance in Caenorhabditis elegans.PMID 29556089Read ↗

EOR-1/PLZF-regulated WAH-1/AIF sequentially promotes early and late stages of non-apoptotic corpse removalSemantic proximity Read ↗

Live-cell imaging in Caenorhabditis elegans reveals the distinct roles of dynamin self-assembly and guanosine triphosphate hydrolysis in the removal of apoptotic cells.Semantic proximity Read ↗

Understanding the diversity and dynamics of in vivo efferocytosis: Insights from the fly embryoSemantic proximity Read ↗

EFF-1-mediated regenerative axonal fusion requires components of the apoptotic pathway.Semantic proximity Read ↗

Epidermal cells are the primary phagocytes in the fragmentation and clearance of degenerating dendrites in Drosophila.Semantic proximity Read ↗

Intermediate Filaments Associate with Aggresome-like Structures in Proteostressed <i>C. elegans</i> Neurons and Influence Large Vesicle Extrusions as ExophersSemantic proximity Read ↗

Autophagy genes promote apoptotic cell corpse clearance.Semantic proximity Read ↗

Components of the Engulfment Machinery Have Distinct Roles in Corpse Processing.Semantic proximity Read ↗

Phagocytic receptor CED-1 initiates a signaling pathway for degrading engulfed apoptotic cells.Semantic proximity Read ↗

Caenorhabditis elegans Myotubularin MTM-1 Negatively Regulates the Engulfment of Apoptotic CellsSemantic proximity Read ↗

Scrambled Eggs: Apoptotic Cell Clearance by Non-Professional Phagocytes in the Drosophila OvarySemantic proximity Read ↗

C. elegans Rab GTPase activating protein TBC-2 promotes cell corpse degradation by regulating the small GTPase RAB-5.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.