Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Artificial Sweetener Splenda Promotes Gut Proteobacteria, Dysbiosis, and Myeloperoxidase Reactivity in Crohn’s Disease–Like Ileitis

15 Mar 2018

Abstract excerpt

Background: Epidemiological studies indicate that the use of artificial sweeteners doubles the risk for Crohn's disease (CD). Herein, we experimentally quantified the impact of 6-week supplementation with a commercial sweetener (Splenda; ingredients sucralose maltodextrin, 1:99, w/w) on both the severity of CD-like ileitis and the intestinal microbiome alterations using SAMP1/YitFc (SAMP) mice. Methods:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune and Inflammatory Disorders
Share to Gut microbiota and health
Share to Inflammatory Bowel Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29554272
DOI: 10.1093/ibd/izy060

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

The Artificial Sweetener Splenda Promotes Gut Proteobacteria, Dysbiosis, and Myeloperoxidase Reactivity in Crohn’s Disease–Like IleitisPMID 29554272Read ↗

Fungal lysozyme leverages the gut microbiota to curb DSS-induced colitisSemantic proximity Read ↗

Infection and inflammation stimulate expansion of a CD74+ Paneth cell subset to regulate disease progressionSemantic proximity Read ↗

Dietary antioxidant micronutrients alter mucosal inflammatory risk in a murine model of genetic and microbial susceptibility.Semantic proximity Read ↗

SAMP1/YitFc mouse strain: A spontaneous model of Crohnʼs disease-like ileitisSemantic proximity Read ↗

A Super-Aged Microminipig Model for the Development of Health Foods for the Elderly: A Pilot Study on the Administration of Sweet Potato Petiole and Leaf PowderSemantic proximity Read ↗

Sucralose Consumption Ablates Cancer Immunotherapy Response through Microbiome DisruptionSemantic proximity Read ↗

Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel diseaseSemantic proximity Read ↗

Catestatin selects for the colonization of antimicrobial-resistant gut bacterial communitiesSemantic proximity Read ↗

Catestatin Selects for the Colonization of Antimicrobial-Resistant Gut Bacterial CommunitiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.