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Article

Dietary antioxidant micronutrients alter mucosal inflammatory risk in a murine model of genetic and microbial susceptibility.

The Journal of nutritional biochemistry - 1 Apr 2018

Pierre Joseph F, Hinterleitner Reinhard, Bouziat Romain, Hubert Nathan A, Leone Vanessa, Miyoshi Jun, Jabri Bana, Chang Eugene B

Abstract excerpt

Inflammatory bowel diseases (IBD) are caused by the convergence of microbial, environmental, and genetic factors. Diet significantly alters these interactions by affecting both the host and microbiome. Using a mucosal inflammatory model that resembles the human condition of ileal pouchitis, we investigated the effects of Control (CONT) or Antioxidant (AOX) diet, containing pharmacologically relevant levels of 4...

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Identifiers

PMID: 29331497
DOI: 10.1016/j.jnutbio.2017.12.002
PMCID: PMC5866768

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MPO

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