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Article

CR1 gene polymorphisms in Chinese patients with paroxysmal nocturnal hemoglobinuria.

Gene - 15 Jun 2018

Long Zhangbiao, Du Yali, Li Hongmin, Han Bing

Abstract excerpt

Patients with paroxysmal nocturnal hemoglobinuria (PNH) who have minor allele of the complement receptor 1 (CR1) gene, displayed more sub-optimal responder to eculizumab compared with major allele. To investigate polymorphism of the CR1 gene in Chinese patients with PNH and its correlation with clinical features and the potential impact on eculizumab efficiency, we genotyped CR1 rs2274567, rs3811381 and the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29551496
DOI: 10.1016/j.gene.2018.03.037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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