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Article

[Genetic variants in C5 and poor response to eculizumab].

[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jul 2015

Nishimura Jun-Ichi

Abstract excerpt

This review summarizes the presentation entitled "Genetic variants in C5 and poor response to eculizumab" (N Engl J Med. 2014; 370: 632-639), given at Symposium 3 entitled "Basic and clinical topics on red blood cell membrane", during the 76th Annual Meeting of the Japanese Society of Hematology. The molecular basis for the poor response to eculizumab in Japanese patients is unclear. Of 345 Japanese patients with...

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Share to Antibodies, Monoclonal, Humanized
Share to Complement C5
Share to Hemoglobinuria, Paroxysmal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

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Identifiers

PMID: 26251149
DOI: 10.11406/rinketsu.56.855

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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