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Article

Progression of early features of spinocerebellar ataxia type 2 in individuals at risk: a longitudinal study.

The Lancet. Neurology - 1 May 2014

Velázquez-Pérez Luis, Rodríguez-Labrada Roberto, Canales-Ochoa Nalia, Montero Jacqueline Medrano, Sánchez-Cruz Gilberto, Aguilera-Rodríguez Raúl, Almaguer-Mederos Luis E, Laffita-Mesa José M

Abstract excerpt

BACKGROUND: The effects of ATXN2 expansion on the nervous system arise before the cerebellar syndrome can be diagnosed; however, progression of the underlying early clinical manifestations is unknown. We aimed to assess progression of the main clinical features in early stages of the spinocerebellar ataxia type 2 (SCA2). METHODS: We did this longitudinal study between Aug 12, 1986, and Sept 3, 2013, in carriers...

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PMID: 24657153
DOI: 10.1016/S1474-4422(14)70027-4

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ATXN2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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