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MBD4frameshift mutation caused by DNA mismatch repair deficiency enhances cytotoxicity by trifluridine, an active antitumor agent of TAS-102, in colorectal cancer cells

15 Nov 2017

Abstract excerpt

// Satoshi Suzuki 1 , Moriya Iwaizumi 1 , Hidetaka Yamada 2 , Tomohiro Sugiyama 1 , Yasushi Hamaya 1 , Takahisa Furuta 3 , Shigeru Kanaoka 4 , Haruhiko Sugimura 2, 7 , Hiroaki Miyajima 1 , Satoshi Osawa 5 , John M. Carethers 6 and Ken Sugimoto 1 1 First Department of Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan 2 Department of Tumor Pathology, Hamamatsu University School of Medicine,...

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PMID: 29545913
DOI: 10.18632/oncotarget.22484

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