Article
Stress-associated endoplasmic reticulum protein 1 (SERP1) and Atg8 synergistically regulate unfolded protein response (UPR) that is independent on autophagy in Candida albicans.
International journal of medical microbiology : IJMM - 1 Apr 2018
Li Jianrong, Yu Qilin, Zhang Bing, Xiao Chenpeng, Ma Tianyu, Yi Xiao, Liang Chao, Li Mingchun
Abstract excerpt
Cellular stresses could activate several response processes, such as the unfolded protein response (UPR), autophagy and oxidative stress response to restore cellular homeostasis or render cell death. Herein, we identified the Candida albicans stress-associated endoplasmic reticulum protein 1 (SERP1), also known as Ysy6, which was involved in endoplasmic reticulum (ER) stress response. We found that deletion of...
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