Article
The malfunction of peroxisome has an impact on the oxidative stress sensitivity in Candida albicans.
Fungal genetics and biology : FG & B - 1 Oct 2016
Chen Yulu, Yu Qilin, Wang Honggang, Dong Yijie, Jia Chang, Zhang Bing, Xiao Chenpeng, Zhang Biao, Xing Laijun, Li Mingchun
Abstract excerpt
The peroxisome plays an essential role in eukaryotic cellular metabolism, including β-oxidation of fatty acids and detoxification of hydrogen peroxide. However, its functions in the important fungal pathogen, C. albicans, remain to be investigated. In this study, we identified a homologue of Saccharomyces cerevisiae peroxisomal protein Pex1 in this pathogen, and explored its functions in stress tolerance....
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