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Roles and applications of autophagy in guarding against environmental stress and DNA damage in Saccharomyces cerevisiae

24 Apr 2025

Abstract excerpt

Saccharomyces cerevisiae (S. cerevisiae), a famous chassis cell factory, often faces various environmental stress conditions like extreme temperature, osmolarity, and nutrient starvation during the fermentation process. Additionally, chromosomal replication and genome editing-assisted metabolic engineering may cause DNA damage to S. cerevisiae. S. cerevisiae has evolved multiple elaborate mechanisms to fend...

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PMID: 40272088
DOI: 10.1111/febs.70112

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