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Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation

21 Mar 2019

Abstract excerpt

Abstract Targeting regulatory signaling pathways that control human bone marrow stromal (skeletal or mesenchymal) stem cell (hBMSC) differentiation and lineage fate determination is gaining momentum in the regenerative medicine field. Therefore, to identify the central regulatory mechanism of osteoblast differentiation of hBMSCs, the molecular phenotypes of two clonal hBMSC lines exhibiting oppositein...

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PMID: 30899078
DOI: 10.1038/s41598-019-41543-0

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