Article
Dual-strain genital herpes simplex virus type 2 (HSV-2) infection in the US, Peru, and 8 countries in sub-Saharan Africa: A nested cross-sectional viral genotyping study.
PLoS medicine - 1 Dec 2017
Johnston Christine, Magaret Amalia, Roychoudhury Pavitra, Greninger Alexander L, Reeves Daniel, Schiffer Joshua, Jerome Keith R, Sather Cassandra, Diem Kurt, Lingappa Jairam R, Celum Connie, Koelle David M, Wald Anna
Abstract excerpt
BACKGROUND: Quantitative estimation of the extent to which the immune system's protective effect against one herpes simplex virus type 2 (HSV-2) infection protects against infection with additional HSV-2 strains is important for understanding the potential for HSV-2 vaccine development. Using viral genotyping, we estimated the prevalence of HSV-2 dual-strain infection and identified risk factors. METHODS AND...
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