Article
Multivariate Pattern Analysis of Genotype-Phenotype Relationships in Schizophrenia.
Schizophrenia bulletin - 20 Aug 2018
Zheutlin Amanda B, Chekroud Adam M, Polimanti Renato, Gelernter Joel, Sabb Fred W, Bilder Robert M, Freimer Nelson, London Edythe D, Hultman Christina M, Cannon Tyrone D
Abstract excerpt
Genetic risk variants for schizophrenia have been linked to many related clinical and biological phenotypes with the hopes of delineating how individual variation across thousands of variants corresponds to the clinical and etiologic heterogeneity within schizophrenia. This has primarily been done using risk score profiling, which aggregates effects across all variants into a single predictor. While effective,...
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