Article
Multifaceted genomic risk for brain function in schizophrenia.
NeuroImage - 16 Jul 2012
Chen Jiayu, Calhoun Vince D, Pearlson Godfrey D, Ehrlich Stefan, Turner Jessica A, Ho Beng-Choon, Wassink Thomas H, Michael Andrew M, Liu Jingyu
Abstract excerpt
Recently, deriving candidate endophenotypes from brain imaging data has become a valuable approach to study genetic influences on schizophrenia (SZ), whose pathophysiology remains unclear. In this work we utilized a multivariate approach, parallel independent component analysis, to identify genomic risk components associated with brain function abnormalities in SZ. 5157 candidate single nucleotide polymorphisms...
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