Article
Phenotypic and genetic analysis of cognitive performance in Major Depressive Disorder in the Generation Scotland: Scottish Family Health Study.
Translational psychiatry - 13 Mar 2018
Meijsen Joeri J, Campbell Archie, Hayward Caroline, Porteous David J, Deary Ian J, Marioni Riccardo E, Nicodemus Kristin K
Abstract excerpt
Lower performances in cognitive ability in individuals with Major Depressive Disorder (MDD) have been observed on multiple occasions. Understanding cognitive performance in MDD could provide a wider insight in the aetiology of MDD as a whole. Using a large, well characterised cohort (N = 7012), we tested for: differences in cognitive performance by MDD status and a gene (single SNP or polygenic score) by MDD...
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